Type 1 Diabetes Research



at the conferences:

Bowes A & Kerr D “The effectiveness of a mobile phone based approach for teaching carbohydrate counting in comparison to a standard programme in Type 1 diabetes.” nomination for the “Educational Award”, Diabetes UK conference, Glasgow, UK, Mar 2009.

Bowes A, Partridge H, Knott J & Kerr D “Initiating insulin pump therapy – most of the HbA1c benefit is within the first 6 months.” Diabetes UK conference, London, UK, Apr 2011.

Bowes A “Developing a local pump service”. “Insulin Pump Summit”, Birmingham, UK, Apr 2010. (workshops for HCP with interest in insulin pump therapy).

Everett J, Bowes A, Humprey R & Kerr D “Barriers to improving glycaemia control with insulin pump therapy”. Diabetes UK conference, Liverpool, UK, Mar 2010.

HypoCOMPASS (T1 Diabetes Research study)

What is this study about?

This is multicentre randomised control trial funded by Diabetes UK. Bournemouth is one of the five centres in the UK taking part in this trial.

HypoCOMPASS is aimed at people with type 1 diabetes who have reduced awareness of low blood glucose levels (hypoglycaemia). Unawareness of low blood glucose can lead to severe hypoglycaemia which is highly dangerous and may result in collapse without warning, fits, or even sudden death. The purpose of the study is to assess whether awareness of falling glucose can be restored by using modern insulin, insulin pumps and continuous blood glucose meters.

BDEC Research Centre recruited 18 participants (recruitment completed in June 2011) who are randomised to receive either an insulin pump or multiple daily insulin injection treatments, with or without real time continuous glucose monitoring. Participants are provided with intensive support to help manage their diabetes and is aimed to improve the patients’ overall long term diabetes control.

How will this study help people with type 1 diabetes?

Severe hypoglycaemia shows to be one of the key factors responsible for poor glycaemic control in people with Type 1 Diabetes. Poor glycaemic control leads to long-term complications such as kidney, eye and heart disease. Severe hypoglycaemia affects up to 30% of individuals with T1DM and is one of the most feared complications since it can result in collapse without warning, fits, or even sudden death. To avoid severe hypoglycaemia people often choose to run their blood glucose higher than necessary to avoid possibility of hypos as fear of hypos are very difficult to overcome. This study will give us a better understanding about the best ways of treating people with Type 1 diabetes with impaired hypo unawareness.